Dry Fractionation Approach in Concentrating Tocopherols and Tocotrienols from Palm Fatty Acid Distillate: A Green Pretreatment Process for Vitamin E Extraction

Palm fatty acid distillate (PFAD) is a rich source of vitamin E. As compared to other vegetable oil, PFAD has higher tocotrienol (70–80%) over tocopherol content, which makes it a valuable source for vitamin E extraction. Current vitamin E extraction methods are not sustainable due to the intensive usage of chemical and high operational cost. Hence, the present study investigated for the first time using dry fractionation process as a green and economical pretreatment method for separating solid fraction (stearin) and liquid fraction (olein) in order to concentrate vitamin E from PFAD in olein fraction. We examined the dry fractionation conditions: crystallization ending temperature (36–44 °C), cooling rate (0.3 and 1.5°C min⁻¹), stirring speed (20–125 rpm), and holding time (0–60 min) on the composition of unsaturated and saturated fatty acids as well as vitamin E content in liquid fraction (olein) and solid fraction (stearin) using gas chromatography and high performance liquid chromatography, respectively. In most of these conditions, vitamin E was ultimately higher in olein fraction as compared to stearin fraction, which is correlated with the high degree of unsaturation. Under a cooling rate of 0.3°C min⁻¹, 90 rpm stirring speed, and ending crystallization of 38 °C, the highest vitamin E rich olein fraction was attained with 1479 ± 10.51 ppm in 50 g olein fraction as compared to 1366 ± 7.94 ppm in 500 g of unfractionated PFAD.     

小像元红外探测器读出电路设计研究

介绍了基于SMIC 0.18 μm 3.3 V工艺设计研究的第一款小像元红外探测器读出电路,间距10 μm,规模1024×1024。文章详细介绍了像素输入级以及列级、输出级运放的设计,为提高线性摆伏,设计选用了低阈值NMOS管nmvt 33,仿真分析证明低阈值管nmvt 33的噪声性能优于普通管n 33；版图设计对关键信号线和敏感点采取隔离处理措施,对像元间串扰进行了仿真分析,有效控制了信号串扰。电路经测试使用各项功能正常,最大电荷处理能力达到4.3 Me-,动态范围≥65 dB,读出速率达到10 MHz,性能指标满足设计要求。     

Dhh1 is a member of the SESA network

The correct separation of chromosomes during mitosis is necessary to prevent genetic instability and aneuploidy, which are responsible for cancer and other diseases, and it depends on proper centrosome duplication. In a recent study, we found that Smy2 can suppress the essential role of Mps2 in the insertion of yeast centrosome into the nuclear membrane by interacting with Eap1, Scp160, and Asc1 and designated this network as SESA (S my2, E ap1, S cp160, A sc1). Detailed analysis showed that the SESA network is part of a mechanism which regulates translation of POM34 mRNA. Thus, SESA is a system that suppresses spindle pole body duplication defects by repressing the translation of POM34 mRNA. In this study, we performed a genome-wide screening in order to identify new members of the SESA network and confirmed Dhh1 as a putative member. Dhh1 is a cytoplasmic DEAD-box helicase known to regulate translation. Therefore, we hypothesized that Dhh1 is responsible for the highly selective inhibition of POM34 mRNA by SESA.     

大红山铜矿285中段连续开采中胶结矿柱经济分析

大红山铜矿285中段铜铁合采区原矿品位较低,采用胶结充填体置换矿柱开采可能亏损,矿山未建立胶结充填体置换矿柱开采的利润测算方法。利用285中段铜铁合采区标准矿块测算胶结矿柱开采的直接成本,结合中段建设费用分摊和销售费用,建立胶结矿柱开采的利润测算方法,最终完成285中段胶结矿柱开采的利润测算,为胶结矿柱开采提供指导依据。     

低速冲击下的界面响应和磨损行为*

为探究低速冲击下界面响应与磨损行为之间的联系，开展多周次的低速冲击磨损实验；通过分析冲击过程中的接触力峰值、接触时长、接触力冲量、动能耗散等，研究冲击速度对接触界面的力学响应的影响；通过对冲击磨痕的磨损轮廓和形貌、磨损体积的检测分析，以及对磨痕区域元素组分变化的测试，研究冲击速度对接触界面磨损损伤行为的影响。结果表明：冲击速度的增加会导致接触界面在更短的时间内受到更强烈的力学作用；能量吸收率对冲击速度的变化不敏感，但冲击速度的提高会导致单位能量造成的磨损损伤逐渐降低；冲击磨痕可分为以塑性变形和以剥层磨损为主要损伤形式的2种区域；磨损区内经历了严重的摩擦氧化，并随着冲击速度的增加发生冲击副材料转移。因此，冲击速度越高，接触界面间的摩擦越剧烈，形成的表面氧化层避免了冲击副与基底材料的直接接触，延缓了磨损损伤的进一步发展。     

矿井煤与瓦斯突出危险性模糊综合评价方法研究

采用模糊综合评价方法建立模糊数学模型，对矿井煤与瓦斯突出危险性进行分析。在矿山地质调查的基础上，建立矿井煤与瓦斯突出危险性数据库，针对矿山开采与矿山安全的关系建立数学模型，在单一因素评价的基础上进行多因素的模糊综合评价，为矿山安全生产和科学决策提供依据。     

大倾角特厚煤层综放支架防倒防滑安全保障技术

基于古山矿三井大倾角特厚煤层的地质条件,围绕综放面装备防倒防滑的技术难点,从液压支架结构、工作面布置方式、放煤工艺、工作面管理等方面进行了研究,并制定了安全保障技术。主要保障技术:端头3架组成锚固站,作为工作面支架纵向稳定性的基础;支架安装高强度双侧可调活动侧护板,并设置底座调节机构;工作面采用"倾斜-圆弧过渡-水平"的布置方式,减小工作面机头坡度,保证机头支架的稳定性;通过放煤工艺优化模拟,确定采用"单向割煤,二采一放"的放煤方式,以控制支架下滑;沿着工作面倾斜方向,工作面上部由上而下放煤以保持支架的稳定性;工作面其他地段由下而上放煤有利于提高顶煤回收率。工业性试验表明,综放面设备稳定性良好,顶煤回收率达80%,实现了大倾角综放面的安全高效回采,对于类似地质条件的综放装备防倒防滑具有借鉴意义。     

砂浆片局压法推定混凝土砖砌体中砂浆强度的试验研究

现行国家标准GB/T50315—2011《砌体工程现场检测技术标准》所列各技术方法仅适用于烧结普通砖及烧结多孔砖砌体中砂浆强度的推定,而混凝土普通砖与多孔砖砌体中砂浆强度的现场检测方法目前缺乏相应的标准依据。通过采用砂浆片局压法推定混凝土普通砖与多孔砖砌体中砂浆强度的试验研究,验证砂浆片局压法推定烧结普通砖砌体中砂浆强度的换算公式,并提出砂浆片局压法推定混凝土普通砖和多孔砖砌体中砂浆强度的换算方法及测强公式。     

The Effects of the CCR6/CCL20 Biological Axis on the Invasion and Metastasis of Hepatocellular Carcinoma

Chemokines and their receptors have recently been shown to play major roles in cancer metastasis. Chemokine receptor 6 (CCR6) and its ligand, CCL20, were highly expressed in a variety of human cancers. In our present study, we aimed to clarify whether CCR6/CCL20 was correlated with the migration of hepatocellular carcinoma (HCC). RT-PCR and Western blot results showed that CCR6 was overexpressed in different invasive potential HCC cell lines (p < 0.05), while the expression of CCL20 had no obvious difference (p > 0.05). CCR6 was suppressed by siRNA in HCCLM6, and then the biological behaviors of HCCLM6 cells were observed. The results showed that the CCR6/CCL20 biological axis increased the capacity of proliferation and adhesion, as well as the chemotactic migration and the level of cytokines related to degraded extracellular matrix. In conclusion, these findings indicate that CCR6 indeed participates in regulating the migration and invasion of HCC, and it might become a prognostic factor of HCC.     

增进城市地区生物多样性——以新加坡模式为例

自 1963 年以来,新加坡开展实施了绿化计划,并经历了从“花园城市”到“花园中的亲生态城市”的演变。为了在新加坡实现生物多样性保护,国家公园局制定了自然保护蓝图,重点介绍该规划实施的关键是利用技术创新。新加坡城市生物多样性指数是一种评价生物多样性成效的自我评估工具,已在全球范围内的多个城市得到应用。