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排序方式: 共有292条查询结果,搜索用时 31 毫秒
1.
Jennie O'Loughlin Silvia Napolitano Fahad Alkhathami Cillian O'Beirne Daniel Marhöfer Megan O'Shaughnessy Prof. Orla Howe Prof. Matthias Tacke Dr. Marina Rubini 《Chembiochem : a European journal of chemical biology》2021,22(6):1093-1098
Antibiotic resistance is a growing problem for public health and associated with increasing economic costs and mortality rates. Silver and silver-related compounds have been used for centuries due to their antimicrobial properties. In this work, we show that 1,3-dibenzyl-4,5-diphenyl-imidazol-2-ylidene silver(I) acetate/NHC*-Ag-OAc (SBC3) is a reversible, high affinity inhibitor of E. coli thioredoxin reductase (TrxR; Ki=10.8±1.2 nM). Minimal inhibition concentration (MIC) tests with different E. coli and P. aeruginosa strains demonstrated that SBC3 can efficiently inhibit bacterial cell growth, especially in combination with established antibiotics like gentamicin. Our results show that SBC3 is a promising antibiotic drug candidate targeting bacterial TrxR. 相似文献
2.
Almuashi Mohammed Hashim Siti Zaiton Mohd Yusoff Nooraini Syazwan Khairul Nizar Ghabban Fahad 《Multimedia Tools and Applications》2022,81(27):39311-39342
Multimedia Tools and Applications - Analysis of facial images decoding familial features has been attracting the attention of researchers to develop a computerized system interested in determining... 相似文献
3.
Water Resources Management - Climate change will modify the spatio-temporal variation of hydrological variables worldwide, potentially leading to more extreme events and hydraulic infrastructure... 相似文献
4.
Fahad A. Alharthi M. Shashank Shashikanth J Viswantha R Abdulaziz Ali Alghamdi JariS. Algethami Mabkhoot A. Alsaiari Mohammed S. Jalalah Nagaraju Ganganagappa 《Ceramics International》2021,47(7):10242-10249
The high capacity anode material is required to replace the most commonly used anode - graphite to keep up the global demand to achieve the goal. Multi-metal oxide has gained keen attention for its higher theoretical capacity and relatively stable than a single metal oxide. α-SnWO4 has a theoretical capacity of 850 mAh g?1 which is greater than graphite (372 mAh g?1). α-SnWO4 has been synthesized through low-temperature hydrothermal method using tin chloride and sodium tungstate as a precursor in acidic medium (succinic acid) at 200 °C for 12 h. The obtained product has been characterized using various analytical tools such as XRD, FT-IR, UV-DRS, BET, PL, SEM, and HR-TEM. XRD analysis shows the orthorhombic phase with a crystallite size of ~25 nm α-SnWO4has been examined as an electrode material for Li-ion battery (LIB) and displays an initial discharge capacity of 985 mAh g?1. Columbic efficiency close to 100% has been observed for 100 cycles. The stability of the electrode material was studied at different C-rates. Band-gap calculated using UV-DRS (Eg = 1.9 eV) shows that α-SnWO4 is a good candidate for photocatalytic degradation. Results of the photocatalytic experiment using methylene blue (MB) as a model pollutant in an aqueous medium shows good results. The above applications show that α-SnWO4 is multifunctional materials for diverse applications. 相似文献
5.
Saint Martin Marie-Judith Orlhac Fanny Akl Pia Khalid Fahad Nioche Christophe Buvat Irène Malhaire Caroline Frouin Frédérique 《Magma (New York, N.Y.)》2021,34(3):355-366
Magnetic Resonance Materials in Physics, Biology and Medicine - Quantitative analysis in MRI is challenging due to variabilities in intensity distributions across patients, acquisitions and... 相似文献
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Abderrahim Titi Mouslim Messali Rachid Touzani Mohammed Fettouhi Abdelkader Zarrouk Nabil Al-Zaqri Ali Alsalme Fahad A. Alharthi Amjad Alsyahi Ismail Warad 《International journal of molecular sciences》2020,21(22)
A new double-open-cubane core Cd(II)-O-Cu(II) bimetallic ligand mixed cluster of type [Cl2Cu4Cd2(NNO)6(NN)2(NO3)2].CH3CN was made available in EtOH/CH3CN solution. The 1-hydroxymethyl-3,5-dimethylpyrazole (NNOH) and 3,5-dimethylpyrazole (NNH) act as N,O-polydentate anion ligands in coordinating the Cu(II) and Cd(II) centers. The structure of the cluster in the solid state was proved by XRD study and confirmed in the liquid state by UV-vis analysis. The XRD result supported the construction of two octahedral and one square pyramid geometries types around the four Cu(II) centers and only octahedral geometry around Cd(II) two centers. Interestingly, NNOH ligand acts as a tetra-µ3-oxo and tri-µ2-oxo ligand; meanwhile, the N-N in NNH acts as classical bidentate anion/neutral ligands. The interactions in the lattice were detected experimentally by the XRD-packing result and computed via Hirschfeld surface analysis (HSA). The UV-vis., FT-IR and Energy Dispersive X-ray (EDX), supported the desired double-open cubane cluster composition. The oxidation potential of the desired cluster was evaluated using a 3,5-DTB-catechol 3,5-DTB-quinone as a catecholase model reaction. 相似文献
8.
Rizwan Ullah Khan Haojie Yu Li Wang Lisong Teng Zain-ul-Abdin Ahsan Nazir Shah Fahad Tarig Elshaarani Fazal Haq Di Shen 《应用聚合物科学杂志》2020,137(46):49424
The development of safe drug carriers is cardinal in cancer therapy, which can target the cancer cells and release the loaded drug on-demand without damaging the healthy cells of the body. In our work, we synthesized three different biodegradable polymers, poly[(ethyl aminobezoate) (ethyl glycinato) phosphazenes] (PABGPs), in different mole ratio of side groups. The successful synthesis of these PABGPs was confirmed by 1H NMR, 31P NMR, FT-IR, and gel permeation chromatography. These PABGPs were fabricated into drug (camptothecin, CPT, a hydrophobic anticancer drug) loaded nanoparticles. These drug-loaded nanoparticles showed good drug release behaviors under normal physiological conditions (pH 7.4 and temperature 37°C). These PABGPs-based nanoparticles may find their application as effective drug carriers for cancer therapy. 相似文献
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10.
Ahmet Sarı Mohammed Ouikhalfan Hassan Chehouani Gökhan Hekimoğlu Alper Bicer Amir Al-Ahmed Fahad A. Al-Sulaiman Vineet Veer Tyagi 《Polymer Engineering and Science》2020,60(5):909-916
In this work, polyethylene glycol (PEG) as a phase change material (PCM) was incorporated with palygorskite (Pal) clay to develop a novel form-stable composite PCM (F-SCPCM). The Pal/PEG(40 wt%) composite was defined as F-SCPCM and characterized using SEM/EDS, FT-IR, XRD, DSC, and TGA techniques. The DSC results revealed that the F-SCPCM has a melting temperature of 32.5°C and latent heat capacity of 64.3 J/g for thermal energy storage (TES) applications. Thermal cycling test showed that the F-SCPCM had good cycling thermal/chemical stability after 500 cycles. The TGA data proved that that both cycled and non-cycled F-SCPCMs had considerable high thermal durability. Consequently, the created F-SCPCM could be considered as an additive material for production of green construction components with TES capability. POLYM. ENG. SCI., 60:909–916, 2020. © 2020 Society of Plastics Engineers 相似文献