A mathematical analysis of the effects of Hebbian learning rules on the dynamics and structure of discrete-time random recurrent neural networks

We present a mathematical analysis of the effects of Hebbian learning in random recurrent neural networks, with a generic Hebbian learning rule, including passive forgetting and different timescales, for neuronal activity and learning dynamics. Previous numerical work has reported that Hebbian learning drives the system from chaos to a steady state through a sequence of bifurcations. Here, we interpret these results mathematically and show that these effects, involving a complex coupling between neuronal dynamics and synaptic graph structure, can be analyzed using Jacobian matrices, which introduce both a structural and a dynamical point of view on neural network evolution. Furthermore, we show that sensitivity to a learned pattern is maximal when the largest Lyapunov exponent is close to 0. We discuss how neural networks may take advantage of this regime of high functional interest.     

Systematic review of the relationship between quick returns in rotating shift work and health-related outcomes

A systematic literature search was carried out to investigate the relationship between quick returns (i.e. 11.0 hours or less between two consecutive shifts) and outcome measures of health, sleep, functional ability and work–life balance. A total of 22 studies published in 21 articles were included. Three types of quick returns were differentiated (from evening to morning/day, night to evening, morning/day to night shifts) where sleep duration and sleepiness appeared to be differently affected depending on which shifts the quick returns occurred between. There were some indications of detrimental effects of quick returns on proximate problems (e.g. sleep, sleepiness and fatigue), although the evidence of associations with more chronic outcome measures (physical and mental health and work–life balance) was inconclusive.

Practitioner Summary: Modern societies are dependent on people working shifts. This study systematically reviews literature on the consequences of quick returns (11.0 hours or less between two shifts). Quick returns have detrimental effects on acute health problems. However, the evidence regarding effects on chronic health is inconclusive.     

Linear optimal control strategies for production systems with a discrete-event demand pattern

A class of production systems are considered in this paper with the aim of determining closed-loop strategies providing the production effort as functions of the system state. The key feature of the considered class of systems is that the demand and the way it is satisfied are asynchronous sequences of part requests and instantaneous withdrawals, respectively, generated by discrete-event processes, whereas the production process has continuous-time dynamics. The optimization problem, whose objective is to minimize inventory and lateness costs, is restated as an optimal control problem by exploiting some structural properties of the optimal solution. Then, optimal closed-loop strategies are found with dynamic programming techniques.     

Two-step purification strategy for enhanced recovery of recombinant hepatitis B surface antigen from Pichia pastoris

Univariate screening on factors affecting the purification performance of recombinant hepatitis B surface antigen (HBsAg) on ion exchange chromatography (IEC) and size exclusion chromatography (SEC) and the establishment of a two-step purification strategy were performed. Amongst four IEC adsorbents examined, the use of Q Sepharose XL IEC adsorbent under optimized conditions together with optimized SEC purification was able to efficiently purify HBsAg. An established purification strategy comprising the two techniques further demonstrated adaptability for scale-up operations with a final total purification factor (PF) of 94.82 ± 16.20, HBsAg purity of 95.48% and recovery yield of 78.07%.     

Effects of rotation and feedback control on Bénard–Marangoni convection

The effect of a feedback control on the onset of steady and oscillatory Bénard–Marangoni instability in a rotating horizontal fluid layer is considered theoretically using linear stability theory. It is demonstrated that generally the critical Marangoni number for transition from the no-motion (conduction) to the motion state can be drastically increased by the combined effects of feedback control and rotation. The role of the controller gain parameter on the Pr-Ta and Pr-R/R_c parameter spaces, dividing stability domains into which either steady or oscillatory convection is preferred, is determined.     

Quality of Sour Cream Packaged in Cups with Different Light Barrier Properties Measured by Fluorescence Spectroscopy and Sensory Analysis

ABSTRACT:  In this study, photooxidation of sour cream packaged in cups with different light barrier properties was investigated. The sour cream was light exposed for 36 h with a standard fluorescent light tube, simulating storage conditions in many Norwegian grocery stores. Three different cups were evaluated: a white cup, a cup with medium light barrier (LB), and a cup with high LB. The quality of the sour cream was evaluated by sensory analysis and front face fluorescence spectroscopy. The sour cream stored in white cups became very rancid during the light exposure, with a rancid flavor score of 7.8 on a scale from 1 to 9, where 9 is the highest intensity. Cups with high LB gave best protection against the light. The sensory assessors could not distinguish between sour cream stored in cups with high LB and sour cream stored in the dark. The rancid flavor intensity for the cups with medium LB was significantly different ( P  < 0.05) from both the white cup and the cup with high LB. The sensory flavor intensities indicated that with 36 h of light exposure, only a cup with high LB will protect the sour cream sufficiently. The fluorescence measurements corresponded well with the sensory analysis as the photosensitizers were somewhat degraded for sour cream stored in cups with medium LB and most degraded in the white cups. For the cups with high LB, the fluorescence peaks that originated from the photosensitizers were all intact.
PRACTICAL APPLICATION: Dairy products such as sour cream will develop off-odor and taste faults ("sunlight taste") in a few hours if exposed to sufficient fluorescent lightning in the grocery stores. A light barrier can be incorporated in the packaging material to protect the dairy products from the light. Our experiment showed that the incorporation of a black pigment into 1 of the 3 plastic layers in the cup for packaging of sour cream protected the sour cream from degradation when exposed to light.     

Brightness-dependent Tarpley model for global solar radiation estimation using GOES satellite images: Application to Uruguay

A statistical model based on Tarpley’s original solar irradiation model is proposed and evaluated using data from seven new ground stations in Uruguay. The model estimates hourly global solar irradiation on a horizontal surface using GOES-East satellite images. We show that the introduction of a simple brightness dependence in the model parameters drastically improves the accuracy of the estimates. The implementations of the original and the improved models are explained in detail. For each case, the parameters are adjusted using controlled quality solar irradiation data and a comprehensive performance analysis, on an hourly and daily basis, is carried out using data from independent measurement sites. The relative RMS deviations for the estimates of the brightness-dependent model are 7.1% for the daily estimates and 14.0% for the hourly estimates, relative to the mean of the measurements. This represents a reduction of approximately 45% (daily) and 25% (hourly) in the relative RMS deviations of the original model. The improved model provides a good balance between simplicity and accuracy.     

Questioning the Living/Nonliving Dichotomy: Evidence From a Patient With an Unusual Semantic Dissociation.

In this article the authors describe a patient (J.P.) whose category-specific naming deficit eluded the classical dichotomies between living versus nonliving items or visual versus functional attributes. At age 22, he had herpes simplex encephalitis followed by a left temporal lobectomy. J.P. was tested on measures of visual perception, category naming, fluency, and name-picture matching. He showed a severe impairment naming and identifying fruits, vegetables, and musical instruments. His performance with animals and birds was spared inconsistently, meaning that even the preserved categories were, at some point, affected. J.P.'s unusual deficit supports the hypothesis that semantic knowledge is organized in the brain on the basis of object properties, which can cut across the living-nonliving categorical distinction. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Superconducting shields for alternating magnetic fields

This paper describes a shield to guard a dc superconducting field from an ac field.