Analysis of Temperature Effect in Quadruple Gate Nano-scale FinFET

Silicon - Quadruple gate FinFET is a promising candidate among other multi-gate MOS devices due to it’s better scalability and higher short channel effect suppression capability in advanced...     

Solving distribution problems in content-based recommendation system with gaussian mixture model

Applied Intelligence - Recommendation systems play an important role in boosting purchasing consumption for many manufacturers by helping consumers find the most appropriate items. Furthermore,...     

Efficient topography optimization of a washing machine cabinet to reduce radiated noise during the dehydration process

Journal of Mechanical Science and Technology - In modern society, the use of washing machines has increased owing to increased interest in personal hygiene. Over the years, the performance of...     

Incremental Sheet Metal Forming: Numerical Simulation and Rapid Prototyping Process to make an Automobile White‐Body

In order to make an automobile body structure, incremental sheet metal forming is introduced as a rapid prototyping process. Numerical modeling of the process is initially used to predict the deformation of the sheet metal to avoid failure during the incremental forming process using ABAQUS/Explicit finite element code and OYANE's ductile fracture criterion via a VUMAT user material. An automobile CAD model is then designed, and segmented into several parts in order to accommodate the working space of the CNC machine and formability of sheet metal. After that, CAM software is used to generate a tool‐path for making wooden‐dies and all small parts. Finally, a welding process is applied to join all parts which were cut by laser cutting after incremental sheet forming process.     

Biodegradable Nanocapsules as siRNA Carriers for Mutant K‐Ras Gene Silencing of Human Pancreatic Carcinoma Cells

The application of small interfering RNA (siRNA)‐based RNA interference (RNAi) for cancer gene therapy has attracted great attention. Gene therapy is a promising strategy for cancer treatment because it is relatively non‐invasive and has a higher therapeutic specificity than chemotherapy. However, without the use of safe and efficient carriers, siRNAs cannot effectively penetrate the cell membranes and RNAi is impeded. In this work, cationic poly(lactic acid) (CPLA)‐based degradable nanocapsules (NCs) are utilized as novel carriers of siRNA for effective gene silencing of pancreatic cancer cells. These CPLA‐NCs can readily form nanoplexes with K‐Ras siRNA and over 90% transfection efficiency is achieved using the nanoplexes. Cell viability studies show that the nanoparticles are highly biocompatible and non‐toxic, indicating that CPLA‐NC is a promising potential candidate for gene therapy in a clinical setting.     

Effect of harvest date on the nutritional quality and antioxidant capacity in 'Hass' avocado during storage

The effect of harvest date on nutritional compounds and antioxidant activity (AOC) in avocado (Persea americana Mill. cv Hass) fruit during storage was determined. The fruits were harvested at seven different dates and ripened at 25 °C following 21 or 35 days of cold storage. The results indicated that the phenolic and glutathione contents were increased and the ascorbic acid content was not significantly different in early harvested fruit (January to March), and the phenolic, ascorbic acid and glutathione contents were increased slightly and then decreased on late harvested fruit (April to June). Similar trends were observed in the changes of AOC. Furthermore, AOC in early harvested fruit after storage for 35 days was much higher than that in late harvested fruit after storage for 21 days. Therefore, avocado can be harvested earlier for economic benefits according to the market and can keep high nutritional value for human health benefits.