The Versatile Manipulations of Self-Assembled Proteins in Vaccine Design

Protein assemblies provide unique structural features which make them useful as carrier molecules in biomedical and chemical science. Protein assemblies can accommodate a variety of organic, inorganic and biological molecules such as small proteins and peptides and have been used in development of subunit vaccines via display parts of viral pathogens or antigens. Such subunit vaccines are much safer than traditional vaccines based on inactivated pathogens which are more likely to produce side-effects. Therefore, to tackle a pandemic and rapidly produce safer and more effective subunit vaccines based on protein assemblies, it is necessary to understand the basic structural features which drive protein self-assembly and functionalization of portions of pathogens. This review highlights recent developments and future perspectives in production of non-viral protein assemblies with essential structural features of subunit vaccines.     

Low Cost Portable Solution for Real-Time Complete Detection and Analysis of Heart Sound Components

Wireless Personal Communications - Detection of heart sound and analysis is required to determine heart rate, heart sound components (S1, S2 and murmurs), and is an important step to...     

Preface of special issue of CCSN2016

Microsystem Technologies -     

Electricity Generation and Wastewater Treatment of Oil Refinery in Microbial Fuel Cells Using Pseudomonas putida

Microbial fuel cells (MFCs) represent a novel platform for treating wastewater and at the same time generating electricity. Using Pseudomonas putida (BCRC 1059), a wild-type bacterium, we demonstrated that the refinery wastewater could be treated and also generate electric current in an air-cathode chamber over four-batch cycles for 63 cumulative days. Our study indicated that the oil refinery wastewater containing 2213 mg/L (ppm) chemical oxygen demand (COD) could be used as a substrate for electricity generation in the reactor of the MFC. A maximum voltage of 355 mV was obtained with the highest power density of 0.005 mW/cm² in the third cycle with a maximum current density of 0.015 mA/cm² in regard to the external resistor of 1000 Ω. A maximum coulombic efficiency of 6 × 10⁻²% was obtained in the fourth cycle. The removal efficiency of the COD reached 30% as a function of time. Electron transfer mechanism was studied using cyclic voltammetry, which indicated the presence of a soluble electron shuttle in the reactor. Our study demonstrated that oil refinery wastewater could be used as a substrate for electricity generation.     

Comparative study on the structural make-up and mechanical behavior of silicon and silver doped amorphous carbon films

Silicon - Silicon (Si) and silver (Ag) doped amorphous carbon (a-C) thin film were deposited on chrome nitrided 316 LVM stainless steel using filtered cathodic vacuum arc (FCVA) deposition...     

Analysis of Temperature Effect in Quadruple Gate Nano-scale FinFET

Silicon - Quadruple gate FinFET is a promising candidate among other multi-gate MOS devices due to it’s better scalability and higher short channel effect suppression capability in advanced...     

Electrical conductivity of a novel cast 6351 Al–Al4SiC4 in situ composite

In this research work, electrical conductivity of a novel cast 6351 Al–Al₄SiC₄ composite has been studied for varying Al₄SiC₄ particle content (2–7 vol%). Analytical models were developed on the basis of free electron theory and local resistance approach in order to predict electrical conductivity of metal matrix composites. The electrical conductivity of cast 6351 Al–Al₄SiC₄ composite was found to decrease with increasing Al₄SiC₄ content. Overprediction of results and more % deviation of the predicted electrical conductivity from experimental value were observed for local-resistance-approach-based model. However, the model developed on the basis of electron theory considering scattering of electrons at particle–matrix interface accurately predicted the experimental electrical conductivity data.     

Silver(I) Polymer of Tripodal Amine: Synthesis,Structure and Photoluminescence

Starting from tripodal ligand tris-(methyl-imidazole) amine (1) the colourless complex tris-(methyl-imidazole)aminesilver(I)perchlorate (2) has been synthesized, characterized by IR, UV/Vis and ¹HNMR spectroscopic studies and finally solid state structure has been established by single crystal X-ray diffraction studies. A single crystal X-ray structure determination revealed the formation of coordination polymer. The crystal structure possesses weak d¹⁰–d¹⁰ ‘argentophilic’ interactions with Ag–Ag separation (3.348 Å). The weak luminance at 375 nm may be this Ag–Ag weak interaction. The molecule possesses weak H-bonding with C2 and C4H of imidazole with oxygen of ClO₄.     

Special issue on International Conference on Computing,Communication and Sensor Networks (CCSN 2015) held in,Kolkata, India,Dec 24–25, 2015

Microsystem Technologies -