纳米Al2O3粉体材料激光烧结成型基础试验研究

基于激光烧结快速成型技术 ,利用CO2 激光对纳米Al2 O3 粉体材料进行激光烧结成型的试验并用扫描电镜(SEM)和X射线衍射仪等对烧结样品进行分析。结果表明 ,在适当的工艺参数下 ,对Al2 O3 粉体的激光烧结可获得一定形状的、致密的陶瓷块体 ,块体内部晶粒保持在纳米尺度     

新一代长波长红外探测器

文章旨在介绍适应于长波红外焦平面阵列技术发展的红外探测器，由于篇幅的关系，本文着重评述ＩｎＡｓＳｂ应变层超晶格红外探测器和ＧａＡｓ／ＧａＡｌＡｓ多量子阱红外探测器的特点、器件结构、主要制作工艺，性能参数，以及急需要解决的一些问题。     

Growth and characterization of GaAs films deposited on Ge/Si composite substrates by metalorganic chemical vapor deposition

We report the results of studies which have been made on heteroepitaxial layers of GaAs and AlGaAs grown by metalorganic chemical vapor deposition on composite substrates that consist of four different types of heteroepitaxial layered structures of Ge and Ge-Si grown by molecular beam epitaxy on (100)-oriented Si substrates. It is found that of the four structures studied, the preferred composite substrate is a single layer of Ge ∼1 μm thick grown directly on a Si buffer layer. The double-crystal X-ray rocking curves of 2 μm thick GaAs films grown on such substrates have FWHM values as small as 168 arc sec. Transmission electron micrographs of these Ge/Si composite substrates has shown that the number of dislocations in the Ge heteroepitaxial layer can be greatly reduced by an anneal at about 750° C for 30 min which is simultaneously carried out during the growth of the GaAs layer. The quality of the GaAs layers grown on these composite substrates can be greatly improved by the use of a five-period GaAs-GaAsP strained-layer superlattice (SLS). Using the results of these studies, low-threshold optically pumped AlGaAs-GaAs DH laser structures have been grown by MOCVD on MBE Ge/Si composite substrates.     

Direct laser sintering of a copper-based alloy for creating three-dimensional metal parts

Direct laser sintering of metal, as one of the important developments in rapid prototyping technologies, is discussed in this paper. A special copper-based alloy is used for this rapid prototyping process. Experiments on the sintering conditions of this material had been conducted in a self-developed high temperature metal sintering machine. The mechanism of laser sintering for this kind of material was disclosed by SEM analysis of microstructures of sintered parts. The density, surface roughness and mechanical properties of the laser sintering parts due to variation of process parameters were measured and analysed. The effect of process parameters to the accuracy of sintered parts was also investigated. Thus, optimum parameters were obtained for direct laser sintering of three-dimensional metal parts.     

SLS工艺制造的高分子原型材料选择

面向快速铸造工艺的激光选择性烧结（SLS）工艺制造可以制造可烧蚀的高分子快速原型，结合熔模铸造工艺能够实现金属零件的无模快速铸造。选择既适合激光烧结工艺又满足铸造要求的高分子材料是快速铸造工艺的前提。在系统地比较和分析了常用高分子材料的特性．并进行了粉末激光烧结实验后，选择了聚苯乙烯（PS）材料作为快速铸造用SLS原型的粉末原材料。     

AOS SLS空间链路建立协议的仿真设计

针对AOS SLS空-地通信系统,提出了一种空间链路建立协议,设计提供了协议的关键参数,如空-地数据传输协议的数据单元、链路建立成功概率及同步时隙分配等,最后给出详细的链路建立工作流程,并对协议进行仿真,结果表明该协议能够快速有效地建立链路.     

基于SLS原型的快速(重力)铸造工艺

结合SLS快速成形和铸造工艺可以实现金属零件的快速铸造.根据原型材料可熔融和烧失的特性,制定了类似于熔模铸造的快速铸造工艺方案.讨论了快速金属铸件的特点,对快速铸造工艺提出了成功率高、成形性好和性能较高的要求.分析了面向金属零件快速铸造的重力铸造工艺并以实例说明,顶注式浇注系统适用于结构简单且高度不大的快速零件,而阶梯式浇注系统适用于中大型和复杂程度较高的铸件.     

间接法选择性激光烧结技术制备高温特殊复合材料

系统地介绍了覆膜钼粉的制备、烧结成型及后处理工艺技术,总结了间接法选择性激光烧结技术的优缺点,并对该技术进行了展望。     

基于选择性激光烧结方法的金属零件快速制造技术研究

主要研究了通过选择性激光烧结高分子原型件制造金属零件的工艺。通过采用真空压差铸造工艺。结合铸造型壳的制造，成功制造出金属零件。对基于SLS技术的精密铸造过程中的精度控制进行了研究分析，并提出了解决办法。     

Drug self-assembly: A phenomenon at the nanometer scale with major impact in the structure–biological properties relationship and the treatment of disease

Under water-rich conditions, small amphiphilic and hydrophobic drug molecules self-assemble into supramolecular nanostructures. Thus, substantial modifications in their interaction with cellular structures and the ability to reach intracellular targets could happen. Additionally, drug aggregates could be more toxic than the non-aggregated counterparts, or vice versa. Moreover, since self-aggregation reduces the number of effective “monomeric” molecules that interact with the target, the drug potency could be underestimated. In other cases, the activity could be ascribed to the non-aggregated molecule while it stems from its aggregates. Thus, drug self-assembly could mislead from drug throughput screening assays to advanced preclinical and clinical trials. Finally, aggregates could serve as crystallization nuclei. The impact that this phenomenon has on the biological performance of active compounds, the inconsistent and often controversial nature of the published data and the need for recommendations/guidelines as preamble of more harmonized research protocols to characterize drug self-aggregation were main motivations for this review. First, the key molecular and environmental parameters governing drug self-aggregation, the main drug families for which this phenomenon and the methods used for its characterization are described. Then, promising nanotechnology platforms investigated to prevent/control it towards a more efficient drug development process are briefly discussed.