Enhanced wide-activated residual network for efficient and accurate image deblocking

To save bandwidth and storage space as well as speed up data transmission, people usually perform lossy compression on images. Although the JPEG standard is a simple and effective compression method, it usually introduces various visually unpleasing artifacts, especially the notorious blocking artifacts. In recent years, deep convolutional neural networks (CNNs) have seen remarkable development in compression artifacts reduction. Despite the excellent performance, most deep CNNs suffer from heavy computation due to very deep and wide architectures. In this paper, we propose an enhanced wide-activated residual network (EWARN) for efficient and accurate image deblocking. Specifically, we propose an enhanced wide-activated residual block (EWARB) as basic construction module. Our EWARB gives rise to larger activation width, better use of interdependencies among channels, and more informative and discriminative non-linearity activation features without more parameters than residual block (RB) and wide-activated residual block (WARB). Furthermore, we introduce an overlapping patches extraction and combination (OPEC) strategy into our network in a full convolution way, leading to large receptive field, enforced compatibility among adjacent blocks, and efficient deblocking. Extensive experiments demonstrate that our EWARN outperforms several state-of-the-art methods quantitatively and qualitatively with relatively small model size and less running time, achieving a good trade-off between performance and complexity.     

药物相互作用研究在新药研发和审评决策中的应用

药物相互作用改变了剂量效应关系，可能会降低疗效或增加毒性，是临床应用中合并用药治疗时重要的考虑因素。预测具有临床意义的药物相互作用是药物研发过程中获益风险评估的重要环节。本文概述了药物研发过程中药物相互作用研究的目的和意义，体内和体外研究的主要内容；梳理分析了2020年国家药品监督管理局（National Medical Products Administration, NMPA）和美国食品药品监督管理局（Food and Drug Administration, FDA）批准上市的新药药物相互作用研究情况，旨在为我国药物研发过程中药物相互作用研究及其监管审评提供参考。     

成型温度对PBX装药内部质量及性能的影响

针对压制成型的PBX炸药装药，选择CT无损检测、巴西实验和扫描电镜检测等技术，对比研究了室温和加热两种温度下压制成型的炸药装药内部质量、静态力学性能和细观破坏形式。结果表明，加热压制有利于改善炸药装药的内部质量，可避免产生初始损伤，且提高了装药的力学性能。细观尺度上，室温压制成型的装药主要发生界面脱黏破坏，加热压制成型装药的主要破坏形式是穿晶断裂。     

Learning shape and texture progression for young child face aging

Face aging (FA) for young faces refers to rendering the aging faces at target age for an individual, generally under 20s, which is an important topic of facial age analysis. Unlike traditional FA for adults, it is challenging to age children with one deep learning-based FA network, since there are deformations of facial shapes and variations of textural details. To alleviate the deficiency, a unified FA framework for young faces is proposed, which consists of two decoupled networks to apply aging image translation. It explicitly models transformations of geometry and appearance using two components: GD-GAN, which simulates the Geometric Deformation using Generative Adversarial Network; TV-GAN, which simulates the Textural Variations guided by the age-related saliency map. Extensive experiments demonstrate that our method has advantages over the state-of-the-art methods in terms of synthesizing visually plausible images for young faces, as well as preserving the personalized features.     

Secure image encryption scheme using 4D-Hyperchaotic systems based reconfigurable pseudo-random number generator and S-Box

This paper introduces the design of a hardware efficient reconfigurable pseudorandom number generator (PRNG) using two different feedback controllers based four-dimensional (4D) hyperchaotic systems i.e. Hyperchaotic-1 and -2 to provide confidentiality for digital images. The parameter's value of these two hyperchaotic systems is set to be a specific value to get the benefits i.e. all the multiplications (except a few multiplications) are performed using hardwired shifting operations rather than the binary multiplications, which doesn't utilize any hardware resource. The ordinary differential equations (ODEs) of these two systems have been exploited to build a generic architecture that fits in a single architecture. The proposed architecture provides an opportunity to switch between two different 4D hyperchaotic systems depending on the required behavior. To ensure the security strength, that can be also used in the encryption process in which encrypt the input data up to two times successively, each time using a different PRNG configuration. The proposed reconfigurable PRNG has been designed using Verilog HDL, synthesized on the Xilinx tool using the Virtex-5 (XC5VLX50T) and Zynq (XC7Z045) FPGA, its analysis has been done using Matlab tool. It has been found that the proposed architecture of PRNG has the best hardware performance and good statistical properties as it passes all fifteen NIST statistical benchmark tests while it can operate at 79.101-MHz or 1898.424-Mbps and utilize only 0.036 %, 0.23 %, and 1.77 % from the Zynq (XC7Z045) FPGA's slice registers, slice LUTs, and DSP blocks respectively. Utilizing these PRNGs, we design two 16 × 16 substitution boxes (S-boxes). The proposed S-boxes fulfill the following criteria: Bijective, Balanced, Non-linearity, Dynamic Distance, Strict Avalanche Criterion (SAC) and BIC non-linearity criterion. To demonstrate these PRNGs and S-boxes, a new three different scheme of image encryption algorithms have been developed: a) Encryption using S-box-1, b) Encryption using S-box-2 and, c) Two times encryption using S-box-1 and S-box-2. To demonstrate that the proposed cryptosystem is highly secure, we perform the security analysis (in terms of the correlation coefficient, key space, NPCR, UACI, information entropy and image encryption quantitatively in terms of (MSE, PSNR and SSIM)).     

A novel fusion paradigm for multi-channel image denoising

Multi-channel and single-channel image denoising are on two important development fronts. Integrating multi-channel and single-channel image denoisers for further improvement is a valuable research direction. A natural assumption is that using more useful information is helpful to the output results. In this paper, a novel multi-channel and single-channel fusion paradigm (MSF) is proposed. The proposed MSF works by fusing the estimates of a multi-channel image denoiser and a single-channel image denoiser. The performance of recent multi-channel image denoising methods involved in the proposed MSF can be further improved at low additional time-consuming cost. Specifically, the validity principle of the proposed MSF is that the fused single-channel image denoiser can produce auxiliary estimate for the involved multi-channel image denoiser in a designed underdetermined transform domain. Based on the underdetermined transformation, we create a corresponding orthogonal transformation for fusion and better restore the multi-channel images. The quantitative and visual comparison results demonstrate that the proposed MSF can be effectively applied to several state-of-the-art multi-channel image denoising methods.     

An adaptive image steganographic scheme based on Noise Visibility Function and an optimal chaotic based encryption method

Steganography is the science of hiding secret message in an appropriate digital multimedia in such a way that the existence of the embedded message should be invisible to anyone apart from the sender or the intended recipient. This paper presents an irreversible scheme for hiding a secret image in the cover image that is able to improve both the visual quality and the security of the stego-image while still providing a large embedding capacity. This is achieved by a hybrid steganography scheme incorporates Noise Visibility Function (NVF) and an optimal chaotic based encryption scheme. In the embedding process, first to reduce the image distortion and to increase the embedding capacity, the payload of each region of the cover image is determined dynamically according to NVF. NVF analyzes the local image properties to identify the complex areas where more secret bits should be embedded. This ensures to maintain a high visual quality of the stego-image as well as a large embedding capacity. Second, the security of the secret image is brought about by an optimal chaotic based encryption scheme to transform the secret image into an encrypted image. Third, the optimal chaotic based encryption scheme is achieved by using a hybrid optimization of Particle Swarm Optimization (PSO) and Genetic Algorithm (GA) which is allowing us to find an optimal secret key. The optimal secret key is able to encrypt the secret image so as the rate of changes after embedding process be decreased which results in increasing the quality of the stego-image. In the extracting process, the secret image can be extracted from the stego-image losslessly without referring to the original cover image. The experimental results confirm that the proposed scheme not only has the ability to achieve a good trade-off between the payload and the stego-image quality, but also can resist against the statistics and image processing attacks.     

国家级核应急医学救援分队能力评估指标体系的建立与应用

为进一步摸清国家核应急医学救援分队能力建设现状,国家核应急响应技术支持中心建立了评估指标体系、评分标准,对依托苏州大学附属第二医院(核工业总医院)设立的国家核应急医学救援分队开展能力评估。评估重点包括政策法规、组织机构、预案方案、指挥控制、应急设施与装备、应急响应行动和培训演练等7项一级指标。通过评估,摸清了现状,查找了问题,同时对救援方案、物资装备配备及管理、培训演练等国家核应急医学救援分队能力建设以及核应急能力评估等工作提出改进建议。     

超高清电视系统关键技术浅析

本文对国内外的电视技术发展现状进行了充分的研究和分析,并对超高清电视系统的相关图像技术参数进行了分析和介绍。