Cornus officinalis vinegar reduces body weight and attenuates hepatic steatosis in mouse model of nonalcoholic fatty liver disease

This study aimed to determine the main bioactive components of Cornus officinalis vinegar (COV) and assess the effects of COV on the body weight (BW) and hepatic steatosis in a nonalcoholic fatty liver disease (NAFLD) mouse model. Seven-week-old KM female mice were divided into five treatment groups: (1) Normal control (NC) group, (2) high fat diet (HFD) group, (3) low concentration treatment group (3.5% COV), (4) medium concentration treatment group (5.0% COV), and (5) high concentration treatment group (6.5% COV). Mice in the NC group were fed with a normal chow diet, and those in the other four groups were fed with a HFD known for causing obesity for 10 weeks. Then, mice in the three COV treatment groups were orally administered with COV once a day for 6 weeks. Results showed that the contents of loganin and morroniside in COV reached 16.82 and 51.17 µg/ml, respectively, and COV also contained multiple organic acids. COV significantly reduced BW, abdominal fat weight, liver weight, and the levels of glucose, triglyceride, and low-density lipoprotein cholesterol of serum and increased the levels of high-density lipoprotein cholesterol of serum (p < 0.05). COV also improved the liver function and anti-oxidant activity of liver (p < 0.05). COV treatments increased the interleukin-10 expression and reduced the tumor necrosis factor-α expression in the liver tissue of NAFLD mice (p < 0.05). Histopathological observation revealed that COV suppressed hepatic lipid accumulation and steatosis. The results suggest that COV may contribute to the alleviation of NAFLD and obesity.     

涂装车间节水方案企划与实施

某涂装车间在现有节水措施的基础上，通过企划与实施一系列新的技术及精益管理措施，如，磷化出槽喷淋工艺优化、纯水制水率提升、空调冷凝水回用率提升、中水深度处理回用、用水分级管理等，将新鲜水用量从 15. 2 L/m2降至 11. 3 L/m2，达到涂装行业清洁生产评价指标体系（ 2016版）中的 I级标准 12 L/m²要求，处于国内领先水平。     

Multi-objective layout optimization for an orbital propellant depot

Structural and Multidisciplinary Optimization - The overall layout optimization design of an orbital propellant depot involves the optimization of shape, size, and positions of propellant tanks in...     

Fabrication of crescent-shaped ceramic microparticles based on single emulsion microfluidics

Ceramic microparticles have great potentials in various fields such as materials engineering, biotechnology, microelectromechanical systems, etc. Morphology of the microparticle performs an important role on their application. To date, it remains difficult to find an effective and controllable way for fabricating nonspherical ceramic microparticles with 3D features. This work demonstrates a method that combines UV light lithography and single emulsion opaque-droplet-templated microfluidic molding to prepare the crescent-shaped ceramic microparticles. By tailoring the intensity of UV light and flow rate of fluid, the shapes of microparticles are accordingly tuned. Therefore, varieties of crescent-shaped microparticles and their variations have been fabricated. After sintering, the crescent-shaped alumina ceramic microparticles were obtained. Benefitting from the light absorption and scattering behavior of most ceramic nanoparticles, this system can serve as a general platform to produce crescent-shaped microparticles made from different materials, and hold great potentials for applications in microrobotics, structural materials in MEMS, and biotechnology.     

Catalytic oxidation of CO on mesoporous codoped ceria catalysts:Insights into correlation of physicochemical property and catalytic activity

Codoping approach is an appealing strategy to further improve the catalytic activity of Ce-based catalysts. In the present study,Mn and/or Cu doped ceria solid solutions MnxCuyCe_(1-x-y)O_2,Cu_xCe_(1-x)O_2,Mn_xCe_(1-x)O_2 and pure CeO_2 were prepared by CTAB-assisted hydrothermal method for CO oxidation.XRD, SEM, EDS, BET, Raman, H2-TPR, XPS and in situ DRIFTS techniques were carried out to study the physicochemical properties and to correlate them to the activity. The doped samples maintain the cubic fluorite structure of CeO_2 with high crystallinity and small crystallite size, forming Ce-based solid solutions. The obtained catalysts have large mesoporous structure with average pore size of 10-14 nm. The doped transition metal enhances the oxygen vacancies and improves reducibility of the solids. The synergistic interaction of Mn and Cu codoping induces mo re oxygen vacancies, pro moting the increase of surface adsorbed oxygen and the transfer of bulk oxygen of catalyst, thereby enhancing the catalytic activity for CO oxidation. Besides, the decomposition rate of the carbonate species which is derived from in situ DRIFTS for each catalyst can provide a measure to evaluate its catalytic activity of CO oxidation.     

基于神经网络的实物保护系统综合效能评估研究

目前国内外核设施实物保护系统大多采用路径分析法进行有效性评价,通过计算截住概率来衡量系统的优劣,评估指标单一,未能精确反映系统可靠性、指挥策略、信息安全设计等因素对系统性能的影响。为全面分析实物保护系统综合效能,从影响系统效能因素集出发,采用层次分析法(Analytic Hierarchy Process,AHP)建立实物保护系统综合效能评估指标体系,同时借助BP(Back Propagation)神经网络的非线性复合能力,建立核设施实物保护系统综合效能评估模型,完成了海洋核动力平台实物保护系统综合效能评估。评估结果表明:该BP神经网络评估模型收敛迅速,避免了AHP评估过程中不能满足多数样本集中效应的缺点,且具有较好的自适应性、稳定性,为实物保护效能评估领域提供了一种全新思路。     

VUV photoluminescence properties of KSrPO4:Dy3+ phosphor

White-light-emitting phosphors based on phosphate host matrix, KSrPO_4 doped with Dy~(3+), were prepared by solid state reaction and their VUV luminescent properties were firstly investigated. The excitation band peaking at 125-153 nm corresponding to the absorption of PO_4~(3-) group exhibits very strong absorption. The phosphors emit warm-white luminescence under vacuum ultraviolet excitation of 147 nm, which consists of three main emission peaks located at 475, 570 and 662 nm, respectively.According to the luminescence and color chromaticity of the optimal sample KSrPO_4:1 mol%Dy~(3+),1.3 mol%Li~+, it can be a potential candidate for mercury-free fluorescent lamps.     

Discrimination the geographical origin of Yanchi Tan Lamb with different muscle sections by stable isotopic ratios and elemental profiles

In the study, lamb, feed and soil samples were collected from three regions of China in the year 2017 and 2018. The δ¹³C and δ¹⁵N values in lamb (defatted dry mass and lipids) and grass and the contents of nine elements in lamb, grass and soil were determined. The results indicated that except for Fe, Zn and Rb, most variables of lamb showed significant differences among two or three regions, and the contents of Fe, Sr and Cs showed significant differences between two years, and the contents of Cu and Zn showed significant differences among different muscle sections. Besides, significant correlations were found for δ¹³C between defatted lamb and lipid (r² = 0.973, P < 0.05) and for the element contents between lamb and soil. Finally, four key variables δ¹³C, δ¹⁵N, Sr and Mo were selected through stepwise canonical discriminant analysis with the cross-validation correct classification rate of 99.1%.     

基于Hausdorff距离的光纤陀螺阈值滤波算法

要实现采矿机组的智能化，必须对采矿机械的位姿进行实时准确地控制。由于开采工作面环境复杂，可选用捷联惯性导航技术来实现对采矿机械的监测。光纤陀螺作为捷联惯导系统的核心元件，其随机噪声制约着惯性导航系统的精度。传统的建模滤波及小波消噪方法由于其自身的局限性，不能保证准确性和去噪效果。所以结合经验模态分解（Empirical Mode Decomposition，EMD），提出了Hausdorff距离（Hausdorff Distance，HD）筛选准则与阈值滤波相结合的去噪算法。该算法以本征模态函数（Intrinsic Mode Function，IMF）与原始信号概率密度函数（Probability Density Function，PDF）的Hausdorff距离为判别依据，对所有IMF进行筛选，之后引入阈值对筛选出的IMF进行滤波处理，最后将其与余项重构。通过试验比较了软硬阈值的滤波效果，确定了该算法采用硬阈值。为验证算法的有效性，将该算法与其他3种方法进行比较，仿真信号与实测陀螺静态漂移数据的试验结果表明了该方法的优越性，能够有效降低陀螺的各项随机误差。