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1.
Porous bony scaffolds are utilized to manage the growth and migration of cells from adjacent tissues to a defective position. In the current investigation, the effect of titanium oxide (TiO2) nanoparticles on mechanical and physical properties of porous bony implants made of polymeric polycaprolactone (PCL) is studied. The bio-nanocomposite scaffolds are prepared with composition of nanocrystalline hydroxyapatite (HA) and TiO2 powder using the freeze-drying technique for different weight fractions of TiO2 (0 wt%, 5 wt%, 10 wt%, and 15 wt%). In order to identify the microstructure and morphology of the fabricated porous bio-nanocomposites, the X-ray diffraction (XRD), atomic force microscope (AFM) and scanning electron microscopy (SEM) are employed. Also, the biocompatibility and biodegradability of the manufactured scaffolds are examined by placing them in a simulated body fluid (SBF) for 21 days, their weight and pH changes are measured. The rate of degradation of the PCL-HA scaffold can be controlled by varying the percentage of its constituent components. Due to an increasing growth and activity of bone cells and the apatite formation on the free surface of the fabricated bio-nanocomposite implants as well as their reasonable mechanical properties, they have the potential to be used as a bone substitute. Additionally, with the aid of the experimentally extracted mechanical properties of the scaffolds, the vibrational characteristics of a beam-type implant made of the proposed porous bio-nanocomposites are explored. The results obtained from SEM image indicate that the scaffolds produced by the employed method have high total porosity (70%–85%) and effective porosity. The pore size is obtained between 60 and 200 μm, which is desirable for the growth and propagation of bone cells. Also, it is revealed that the addition of TiO2 nanoparticles leads to reduce the rate of dissolution of the fabricated bio-nanocomposite scaffolds.  相似文献   
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Engineering with Computers - Optimizing the high computational real-world problems is a challenging task that has taken a great deal of efforts in the last decade. The meta-heuristic algorithms...  相似文献   
4.
Water Resources Management - In recent decades, due to groundwater withdrawal in the Kabodarahang region, Iran, Hamadan, hazardous events such as sinkholes, droughts, water scarcity, etc., have...  相似文献   
5.
In situ prolonged delivery of drugs at the site of tumor can be satisfactorily accelerated patient recovery. We compared the effect of temozolomide while incorporated by polycaprolactone nanofibers on the apoptotic behavior of U87 glioma cells. After biocompatibility evaluation of nanofibers by scanning electron microscope and 3-(4,5-dimethylthiazolyl-2)-2,5-diphenyltetrazolium bromide analysis, the apoptosis of U87 cells was evaluated using p53, Bcl2 and Bax genes expression. It was found that nanofiber-temozolomide group showed a greater ability to induce apoptosis as well as have a significantly diminished initial burst release of drug compared with other groups and have promising potential in treating cancer.  相似文献   
6.
In this paper, a 3 to 8 optical decoder was proposed using nonlinear photonic crystal ring resonators. For realizing the 3 to 8 decoder, we combined seven 1 to 2 optical decoders. In the proposed structure, X, Y and Z serve as input ports. By combination of these ports, one can control which output port to be ON. The maximum time delay of the proposed structure is about 6?ps.  相似文献   
7.

Floods are common and recurring natural hazards which damages is the destruction for society. Several regions of the world with different climatic conditions face the challenge of floods in different magnitudes. Here we estimate flood susceptibility based on Analytical neural network (ANN), Deep learning neural network (DLNN) and Deep boost (DB) algorithm approach. We also attempt to estimate the future rainfall scenario, using the General circulation model (GCM) with its ensemble. The Representative concentration pathway (RCP) scenario is employed for estimating the future rainfall in more an authentic way. The validation of all models was done with considering different indices and the results show that the DB model is most optimal as compared to the other models. According to the DB model, the spatial coverage of very low, low, moderate, high and very high flood prone region is 68.20%, 9.48%, 5.64%, 7.34% and 9.33% respectively. The approach and results in this research would be beneficial to take the decision in managing this natural hazard in a more efficient way.

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8.
Mathematical models for single electrode reversible heat and non-isothermal electromotive force (EMF) of a solid oxide fuel cell (SOFC) are developed. These models estimate the volumetric reversible heat generation and EMF of electrochemical reactions, within each electrode at local conditions of temperature and pressure, based on entropy change of half reactions. The resulting equations are thermodynamically consistent. They inherently obey the conservation of energy law as the electrochemical energy released added to the heat of reactions at each electrode equate the enthalpy change of the reacted species. The equations are implemented to model electrodes in a tubular micro- solid oxide fuel cell (TμSOFC). The thermodynamic consistency of the model is numerically confirmed as the enthalpy of the reactants equates the electric energy released by the cell plus the sum of electrode heats plus electrolyte Ohmic heat. The effect of thermal gradients on the cell's overall EMF is found to be negligible. The reversible and irreversible heat generation of each electrode are distinguished. Overall, the anode is found to be endothermic, and the cathode exothermic.  相似文献   
9.
Telecommunication Systems - Queueing models play a significant role in analysing the performance of power management systems in various electronic devices and communication systems. This paper...  相似文献   
10.
Non-destructive measurement of qualitative parameters of agricultural produce is quite beneficial in the postharvest operations. The consequential effect of mechanical damage in citrus fruits is rarely visible in their appearance compared to other commodities. The purpose of this study was to propose a fast, non-destructive method for sweet lemon mechanical damage detection using image processing technique and UV radiation. For this purpose, 135 sweet lemons were tested based on a completely randomized factorial design. In order to examine mechanical damage, the independent variables included drop height, fruit diameter and tempering period (holding time at room temperature after treatment). Fruits were dropped from heights of 2, 2.5 and 3 m onto the ground. Then images were captured under UV light having a wavelength of 365 nm, 1, 3 and 6 days after treatment. The images were sent to a PC and analyzed using MATLAB software. “Green Spot Index” or GSI was defined to show the extent of mechanical damage. Results of the analysis of variance showed that the percentage of green spots on fruit skin is significant at the 1% level considering the main and double interaction effects of drop height and fruit diameter. Green spot index significantly increases with the level of mechanical damage. Accuracy of the developed method in differentiating the bruised and undamaged fruits was found to be 100%.  相似文献   
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